Diphenylhydantoin (Dilantin)투여(投與)가 성견타액선(成犬唾液腺) 및 간조직(肝組織)에 미치는 영향(影響)에 관(關)한 실험적연구(實驗的硏究)
Effects of Diphenylhydantoin on Salivary Gland and Liver Tissue In Experimental Dogs
문동선, 이재현, 김종은,
소속 상세정보
문동선 ( Moon Dong-Sun ) - 서울대학교 치과대학 치주과학교실
이재현 ( Lee Jae-Hyun ) - 서울대학교 치과대학 치주과학교실
김종은 ( Kim Jong-Eun ) - 서울대학교 치과대학 치주과학교실
KMID : 0363019740040010017
Abstract
The purpose of the present experiment is to clarify the effects of the diphenylhydantoin on salivary gland and liver tissue. Twelve young adult dogs of about -6 mouth old with permanent dentition were used as experimental animals. Those animals divided into four groups; Group I Control group; Group II. Local irritatiofl group; Group III Dilantin administered plus local irritation; acid Group IV Dilantin admrini= stered group. Dilantin was given orally with daily dosage of 7 mg per kilo$reh of the body weight. Those animals were sacrificed at intervals of 37,44, and 50 days and fixed in 10% neutro-formalin solution. The tissue was ´prepared in serial section and staining process was made with Hematoxylin-eosin, Vangieson, R. N. A., and P. A. S. staining. The results obtained are summarized as follows; 1. The histologic features of salivary gland and liver tissue showed no difference between the control and the local irritation group. 2. Severe inflammatory changes were
키워드
원문 및 링크아웃 정보
등재저널 정보